Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). The study, which will be published February 8 in the Journal of Experimental Medicine, reveals the distinct roles played by two critical tumor suppressor genes that are commonly mutated in these highly lethal cancers.
A research group from RIKEN and Kyushu University has developed a new type of material, based on ethylene, which exhibits a number of useful properties such as self-healing and shape memory. Remarkably, some of the materials can spontaneously self-heal even in water or acidic and alkali solutions. The new material is based on ethylene, a compound that is the source of much of the plastic in use today.
Researchers studying male and female marmosets have homed in on the primate brain circuitry responsible for individual differences in overall anxiety. Their findings, published in JNeurosci, show that increasing levels of the neurotransmitter glutamate in the hippocampus normalizes anxious monkeys' "fight or flight" response.
If mice grow up in a stimulating environment, for example in large cages with running wheels and labyrinths with several other mice, their brain remains adaptable for longer, ie more plastic.
A new, simple, and inexpensive method that uses ultraviolet light to control particle motion and assembly within liquids could improve drug delivery, chemical sensors, and fluid pumps.
A rapid rise in temperature on ancient Earth triggered a climate response that may have prolonged the warming for many thousands of years, according to scientists.
An old antibiotic, called nifuroxazide, could selectively kill dangerous cells within melanomas, the deadliest type of skin cancer, scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine at the University of Edinburgh have found.
Researchers have sequenced the genomes of over 140,000 women in China, the largest-scale genetic analysis of Chinese people to date, using data from non-invasive prenatal testing (NIPT) to assemble a representative sample of the whole population.
Rice University nanoscientists have demonstrated a new catalyst that can convert ammonia into hydrogen fuel at ambient pressure using only light energy, mainly due to a plasmonic effect that makes the catalyst more efficient.
A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components.
Small Cell Lung Cancer (SCLC) is very aggressive, since the cancer cells not only quickly grow but also easily spread to entire body.
The offspring of radar soldiers exposed to high doses of radiation during their service experience more genetic alterations than families without radiation exposure.
A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever,taken the organoid system and added the third major cell type in the central nervous system--oligodendrocytes--and now have a more accurate representation of cellular interactions that occur during human brain development.
Mongooses remember and reward helpful friends
Are the CDC’s opioid guidelines harming pain patients rather than helping them? Here’s what we know about the CDC’s role in fighting the ongoing public health crisis.
Investigators at the Medical University of South Carolina report in Microbiome that autoantibody production in HIV-positive patients who have undergone antiretroviral therapy is linked to levels of Staphylococcus products in their blood.
With the opioid crisis continuing to rage across the country, many national institutions focused on bolstering public health have leapt forward to provide guidance and assistance to medical professionals.
Low-risk patients undergoing a total hip replacement with a posterior approach can skip the standard hip precautions currently recommended for post-surgical recovery, according to a new study conducted at Hospital for Special Surgery (HSS), in New York City.
New research indicates that colorectal cancer diagnosed at an early age has clinical and genetic features that are different from those seen in traditional colorectal cancer diagnosed later in life. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also revealed certain unique features in especially young patients and those with predisposing conditions.
Pancreatic cancer is a grim diagnosis, with a five-year survival rate of less than 9 percent. To improve those odds, researchers at UPMC and the University of Pittsburgh School of Medicine sought genetic signatures in the largest study of its kind that could be used to better match drugs to patients and for early detection.
Study suggests providing post-discharge transitional care may be key to reducing hospital readmissions, according to the Canadian Journal of Cardiology
The first population-level study on the link between gut bacteria and mental health identifies specific gut bacteria linked to depression and provides evidence that a wide range of gut bacteria can produce neuroactive compounds. Jeroen Raes (VIB-KU Leuven) and his team published these results today in the scientific journal Nature Microbiology.
Scientists at the Higher School of Economics, the Institute of Bioorganic Chemistry of the Russian Academy of Sciences (IBCh RAS), and the Memorial Sloan Kettering Cancer Center created a genetic model that helps to understand how the body restrains autoimmune and oncological diseases.