Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). The study, which will be published February 8 in the Journal of Experimental Medicine, reveals the distinct roles played by two critical tumor suppressor genes that are commonly mutated in these highly lethal cancers.
A research group from RIKEN and Kyushu University has developed a new type of material, based on ethylene, which exhibits a number of useful properties such as self-healing and shape memory. Remarkably, some of the materials can spontaneously self-heal even in water or acidic and alkali solutions. The new material is based on ethylene, a compound that is the source of much of the plastic in use today.
Researchers studying male and female marmosets have homed in on the primate brain circuitry responsible for individual differences in overall anxiety. Their findings, published in JNeurosci, show that increasing levels of the neurotransmitter glutamate in the hippocampus normalizes anxious monkeys' "fight or flight" response.
If mice grow up in a stimulating environment, for example in large cages with running wheels and labyrinths with several other mice, their brain remains adaptable for longer, ie more plastic.
A new, simple, and inexpensive method that uses ultraviolet light to control particle motion and assembly within liquids could improve drug delivery, chemical sensors, and fluid pumps.
A rapid rise in temperature on ancient Earth triggered a climate response that may have prolonged the warming for many thousands of years, according to scientists.
An old antibiotic, called nifuroxazide, could selectively kill dangerous cells within melanomas, the deadliest type of skin cancer, scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine at the University of Edinburgh have found.
Researchers have sequenced the genomes of over 140,000 women in China, the largest-scale genetic analysis of Chinese people to date, using data from non-invasive prenatal testing (NIPT) to assemble a representative sample of the whole population.
Rice University nanoscientists have demonstrated a new catalyst that can convert ammonia into hydrogen fuel at ambient pressure using only light energy, mainly due to a plasmonic effect that makes the catalyst more efficient.
A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components.
Small Cell Lung Cancer (SCLC) is very aggressive, since the cancer cells not only quickly grow but also easily spread to entire body.
The offspring of radar soldiers exposed to high doses of radiation during their service experience more genetic alterations than families without radiation exposure.
A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever,taken the organoid system and added the third major cell type in the central nervous system--oligodendrocytes--and now have a more accurate representation of cellular interactions that occur during human brain development.
Mongooses remember and reward helpful friends
The epidemic levels of physicians reporting burnout dropped modestly in 2017, according to a study by researchers at the Stanford University School of Medicine, the Mayo Clinic and the American Medical Association.
Assessing the accuracy and value of an increasingly popular and free online patient management app, researchers at Johns Hopkins Medicine and other institutions say that physicians with more training and experience perform better in selecting appropriate diagnoses for sample patient scenarios.
Nearly one in ten patients with kidney failure will undergo toe, foot, or leg amputation in their last year of life and during this time, these patients have prolonged stays in health care settings and limited access to hospice services.
NIH-funded study found Neuromelanin-sensitive MRI able to measure dopamine function associated with psychosis
The disease systemic lupus erythematosus (SLE) -- marked by the attack on joints, skin, and kidneys by the body's immune system -- is linked to an abnormal mix of bacteria in the gut. This is according to a new study led by scientists at NYU School of Medicine.
Proteins from adult stem cells might reduce inflammation caused by Acute Respiratory Distress Syndrome
According to a new statement from a panel of national and international experts in gastroenterology, inflammatory bowel disease (IBD) and other areas, interventional (or therapeutic) IBD endoscopy has an expanding role in the treatment of disease and of adverse events from surgery.
Cancer cells are, in some respects, impressive: They can grow relentlessly, sidestep the aging process by becoming immortal, and evade the immune system's persistent attacks. But in the process of acquiring such superpowers, the cells must occasionally relinquish other, more mundane skills--including the ability to produce certain nutrients.
Immune checkpoint stimulator, SA-4-1BBL, as a single agent prevents against multiple types of cancer
Scientists at the University of Colorado Anschutz Medical Campus have implicated a largely hidden part of the human genome in the severity of autism symptoms, a discovery that could lead to new insights into the disorder and eventually to clinical therapies for the condition.