Animal venoms are the subject of study at research center based at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets of diseases and, armed with that knowledge, develop new compounds that can be used as medicines.
Fight or flight, panic, trembling: Our brains are wired to ensure we respond instantly to fear. While that fear response may save our lives in the dangerous moment
A new multi-institution study spearheaded by researchers at Florida State University and the University of California, Los Angeles suggests a tiny protein could play a major role in combating heart failure related to Duchenne muscular dystrophy (DMD), the most common lethal genetic disorder among children.
If the American Cancer Society's projections prove accurate, more people will die from pancreatic cancer than from breast, brain, ovarian or prostate cancer this year.
Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). The study, which will be published February 8 in the Journal of Experimental Medicine, reveals the distinct roles played by two critical tumor suppressor genes that are commonly mutated in these highly lethal cancers.
A research group from RIKEN and Kyushu University has developed a new type of material, based on ethylene, which exhibits a number of useful properties such as self-healing and shape memory. Remarkably, some of the materials can spontaneously self-heal even in water or acidic and alkali solutions. The new material is based on ethylene, a compound that is the source of much of the plastic in use today.
Researchers studying male and female marmosets have homed in on the primate brain circuitry responsible for individual differences in overall anxiety. Their findings, published in JNeurosci, show that increasing levels of the neurotransmitter glutamate in the hippocampus normalizes anxious monkeys' "fight or flight" response.
If mice grow up in a stimulating environment, for example in large cages with running wheels and labyrinths with several other mice, their brain remains adaptable for longer, ie more plastic.
A new, simple, and inexpensive method that uses ultraviolet light to control particle motion and assembly within liquids could improve drug delivery, chemical sensors, and fluid pumps.
A rapid rise in temperature on ancient Earth triggered a climate response that may have prolonged the warming for many thousands of years, according to scientists.
An old antibiotic, called nifuroxazide, could selectively kill dangerous cells within melanomas, the deadliest type of skin cancer, scientists from the Medical Research Council (MRC) Institute of Genetics and Molecular Medicine at the University of Edinburgh have found.
Researchers have sequenced the genomes of over 140,000 women in China, the largest-scale genetic analysis of Chinese people to date, using data from non-invasive prenatal testing (NIPT) to assemble a representative sample of the whole population.
Rice University nanoscientists have demonstrated a new catalyst that can convert ammonia into hydrogen fuel at ambient pressure using only light energy, mainly due to a plasmonic effect that makes the catalyst more efficient.
A team of physicists has devised a novel strategy that uses naturally occurring motions inside the human cell nucleus to measure the physical properties of the nucleus and its components.
Today, the International Osteoporosis Foundation (IOF) released a new report, revealing approximately 80 percent of patients treated in clinics or hospitals following a fracture are not screened for osteoporosis or risk of future falls. Left untreated, these patients are at high risk of suffering secondary fractures and facing a future of pain, disfigurement, long-term disability and even early death.
A new technique for precisely targeting molecules within cells is paving the way for safer medicines that are free of side effects. Researcher J. Julius Zhu, Ph.D. of the University of Virginia School of Medicine, and his colleagues have developed a way to manipulate molecules from compartment to compartment within individual cells.
Researchers from the UK and Denmark have developed a new method to predict the physical stability of drug candidates, which could help with the development of new and more effective medicines for patients. The technology has been licensed to the Cambridge spin-out company TeraView, who is developing it for use in the pharmaceutical industry in order to make medicines that are more easily released in the body.
Simply introducing a default physician order -- a "nudge" -- into electronic health records (EHRs) cut the use of unnecessary daily imaging in half during palliative radiation therapy sessions for patients with advanced cancer, according to a Penn Medicine study published today in JAMA Oncology.
Data sharing by popular health apps is routine and far from transparent, warn experts. Developers should allow users to choose precisely what data are shared and with whom, say researchers.
In this issue of PLOS Medicine, Kathleen Holloway from WHO and David Henry (University of Toronto, Canada) evaluated data on reported adherence to WHO essential medicines practices and measures of quality use of medicines from 56 low and middle income countries for 2002-2008.
ANN ARBOR, MI - Most older Americans take multiple medicines every day. But a new poll suggests they don't get - or seek - enough help to make sure those medicines actually mix safely. That lack of communication could be putting older adults at risk of health problems from interactions between their drugs and between their prescription drugs and other substances such as over-the-counter medicines, supplements, food, and alcohol.
Lugano/Brussels, 9 April 2019 - Shortages of essential cancer medicines have a direct impact on patient care across Europe. To ensure that this issue remains a top priority on the EU policy agenda, ESMO -the leading European professional organisation for medical oncology, collaborated with the European Parliament to organise a cross-partisan event entitled "Shortages of Inexpensive, Essential Medicines: Calling for Tangible Political Commitments in the EU" (9 April, Brussels) (1).
The study of the Novartis Access program in Kenya demonstrates it is possible to evaluate major pharmaceutical companies' access programs using robust, 'gold standard' methods.
ANN ARBOR, MI - Whether it's a rare treat or a weekly routine, spending time with grandchildren brightens life for many older adults. But a new poll suggests many of them could do more to reduce the risk of their medications harming their grandchild.